Nop 4 debug mode (Nop.Web vs IIS Express)

Hi!

I am about to upgrade to version 4.0 and have a question about debug modes. I noticed on Nop.Web properties page that I can choose between profile "Nop.Web" (default) and profile "IIS Express" for debug.

1. What is the difference and which is to prefer?
2. When I choose IIS Express there is a setting to use SSL but when I click on it it creates a port for me, how can I set it manually (I want to use 44300, https://localhost:44300, but can't find where to change it as I could before .net Core).
3. Is there a way to use SSL (port 44300) for debug instead of http when I use the profile Nop.Web instead of IIS Express? (Can't find the setting when I change profile).

Regards Markus