I have NOP 4.1 application running on Azure production. Site is down now with this error.

An error occurred while starting the application.
.NET Core 4.6.27817.01 X86 v4.0.0.0    |   Microsoft.AspNetCore.Hosting version 2.1.1-rtm-30846  
|    Microsoft Windows 10.0.14393    |   Need help?

Not sure how to resolve. Its urgent please any suggestion asap.

Enable log from web.config.

<aspNetCore requestTimeout="23:00:00" processPath="%LAUNCHER_PATH%" arguments="%LAUNCHER_ARGS%" forwardWindowsAuthToken="false" stdoutLogEnabled="true" stdoutLogFile=".\logs\stdout" startupTimeLimit="3600">
  <environmentVariables />
</aspNetCore>

Then check error log in ~/Logs folder.

Thanks for this. As i checked in Log table found the below error.

Access to the path 'D:\home\site\wwwroot\Plugins\bin\SevenSpikes.Nop.Plugins.Core.dll' is denied.

System.UnauthorizedAccessException: Access to the path 'D:\home\site\wwwroot\Plugins\bin\SevenSpikes.Nop.Plugins.Core.dll' is denied.     at System.IO.FileStream.ValidateFileHandle(SafeFileHandle fileHandle)     at System.IO.FileStream.CreateFileOpenHandle(FileMode mode, FileShare share, FileOptions options)     at System.IO.FileStream..ctor(String path, FileMode mode, FileAccess access, FileShare share, Int32 bufferSize, FileOptions options)     at Microsoft.AspNetCore.Mvc.Razor.Compilation.MetadataReferenceFeatureProvider.CreateMetadataReference(String path)     at Microsoft.AspNetCore.Mvc.Razor.Compilation.MetadataReferenceFeatureProvider.PopulateFeature(IEnumerable`1 parts, MetadataReferenceFeature feature)     at Microsoft.AspNetCore.Mvc.ApplicationParts.ApplicationPartManager.PopulateFeature[TFeature](TFeature feature)    
at Microsoft.AspNetCore.Mvc.Razor.Internal.DefaultRazorReferenceManager.GetCompilationReferences()
    at System.Threading.LazyInitializer.EnsureInitializedCore[T](T& target, Boolean& initialized, Object& syncLock, Func`1 valueFactory)     at Microsoft.AspNetCore.Mvc.Razor.Internal.DefaultRazorReferenceManager.get_CompilationReferences()     at Microsoft.AspNetCore.Mvc.Razor.Internal.LazyMetadataReferenceFeature.get_References()     at Microsoft.CodeAnalysis.Razor.CompilationTagHelperFeature.GetDescriptors()     at Microsoft.AspNetCore.Razor.Language.DefaultRazorTagHelperBinderPhase.ExecuteCore(RazorCodeDocument codeDocument)     at Microsoft.AspNetCore.Razor.Language.RazorEnginePhaseBase.Execute(RazorCodeDocument codeDocument)     at Microsoft.AspNetCore.Razor.Language.DefaultRazorEngine.Process(RazorCodeDocument document)     at Microsoft.AspNetCore.Razor.Language.DefaultRazorProjectEngine.ProcessCore(RazorCodeDocument codeDocument)     at Microsoft.AspNetCore.Razor.Language.RazorProjectEngine.Process(RazorProjectItem projectItem)     at Microsoft.AspNetCore.Mvc.Razor.Internal.RazorViewCompiler.CompileAndEmit(String relativePath)    
at Microsoft.AspNetCore.Mvc.Razor.Internal.RazorViewCompiler.OnCacheMiss(String normalizedPath)
--- End of stack trace from previous location where exception was thrown ---  
  at Microsoft.AspNetCore.Mvc.Razor.Internal.DefaultRazorPageFactoryProvider.CreateFactory(String relativePath)
    at Microsoft.AspNetCore.Mvc.Razor.RazorViewEngine.CreateCacheResult(HashSet`1 expirationTokens, String relativePath, Boolean isMainPage)     at Microsoft.AspNetCore.Mvc.Razor.RazorViewEngine.OnCacheMiss(ViewLocationExpanderContext expanderContext, ViewLocationCacheKey cacheKey)     at Microsoft.AspNetCore.Mvc.Razor.RazorViewEngine.LocatePageFromViewLocations(ActionContext actionContext, String pageName, Boolean isMainPage)     at Microsoft.AspNetCore.Mvc.Razor.RazorViewEngine.FindView(ActionContext context, String viewName, Boolean isMainPage)     at Microsoft.AspNetCore.Mvc.ViewEngines.CompositeViewEngine.FindView(ActionContext context, String viewName, Boolean isMainPage)     at Microsoft.AspNetCore.Mvc.ViewFeatures.ViewResultExecutor.FindView(ActionContext actionContext, ViewResult viewResult)     at Microsoft.AspNetCore.Mvc.ViewFeatures.ViewResultExecutor.ExecuteAsync(ActionContext context, ViewResult result)     at Microsoft.AspNetCore.Mvc.ViewResult.ExecuteResultAsync(ActionContext context)     at Microsoft.AspNetCore.Mvc.Internal.ResourceInvoker.InvokeResultAsync(IActionResult result)    
at Microsoft.AspNetCore.Mvc.Internal.ResourceInvoker.InvokeNextResultFilterAsync[TFilter,TFilterAsync]()  
at Microsoft.AspNetCore.Mvc.Internal.ResourceInvoker.Rethrow(ResultExecutedContext context)  
   at Microsoft.AspNetCore.Mvc.Internal.ResourceInvoker.ResultNext[TFilter,TFilterAsync](State& next, Scope& scope, Object& state, Boolean& isCompleted)     at Microsoft.AspNetCore.Mvc.Internal.ResourceInvoker.InvokeResultFilters()     at Microsoft.AspNetCore.Mvc.Internal.ResourceInvoker.InvokeNextResourceFilter()     at Microsoft.AspNetCore.Mvc.Internal.ResourceInvoker.Rethrow(ResourceExecutedContext context)     at Microsoft.AspNetCore.Mvc.Internal.ResourceInvoker.Next(State& next, Scope& scope, Object& state, Boolean& isCompleted)     at Microsoft.AspNetCore.Mvc.Internal.ResourceInvoker.InvokeFilterPipelineAsync()     at Microsoft.AspNetCore.Mvc.Internal.ResourceInvoker.InvokeAsync()     at Microsoft.AspNetCore.Builder.RouterMiddleware.Invoke(HttpContext httpContext)     at StackExchange.Profiling.MiniProfilerMiddleware.Invoke(HttpContext context) in C:\projects\dotnet\src\MiniProfiler.AspNetCore\MiniProfilerMiddleware.cs:line 94     at Nop.Services.Authentication.AuthenticationMiddleware.Invoke(HttpContext context) in E:\Survival\Version 2.0\Libraries\Nop.Services\Authentication\AuthenticationMiddleware.cs:line 79  
   at Microsoft.AspNetCore.Localization.RequestLocalizationMiddleware.Invoke(HttpContext context)  
   at Microsoft.AspNetCore.Session.SessionMiddleware.Invoke(HttpContext context)  
  at Microsoft.AspNetCore.Session.SessionMiddleware.Invoke(HttpContext context)    
at Nop.Core.Http.InstallUrlMiddleware.Invoke(HttpContext context, IWebHelper webHelper)
in E:\Survival\Version 2.0\Libraries\Nop.Core\Http\InstallUrlMiddleware.cs:line 51  
  at Nop.Core.Http.KeepAliveMiddleware.Invoke(HttpContext context, IWebHelper webHelper)
in E:\Survival\Version 2.0\Libraries\Nop.Core\Http\KeepAliveMiddleware.cs:line 50    
at Microsoft.AspNetCore.StaticFiles.StaticFileMiddleware.Invoke(HttpContext context)    
at Microsoft.AspNetCore.StaticFiles.StaticFileMiddleware.Invoke(HttpContext context)  
  at Microsoft.AspNetCore.StaticFiles.StaticFileMiddleware.Invoke(HttpContext context)    
at Microsoft.AspNetCore.StaticFiles.StaticFileMiddleware.Invoke(HttpContext context)    
at Microsoft.AspNetCore.Diagnostics.StatusCodePagesMiddleware.Invoke(HttpContext context)  
  at Microsoft.AspNetCore.Diagnostics.StatusCodePagesMiddleware.Invoke(HttpContext context)    
at Microsoft.AspNetCore.Diagnostics.ExceptionHandlerMiddleware.Invoke(HttpContext context)


Site is hosted on Azure production.
Is any idea on this error. How to resolve on published site.

Did you give folder permission properly?

As the site published on Azure, can you suggest how to provide folder permission?