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5
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55
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07.11.2016
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India
I am using nopcommerce v4.2 but this will worl for all 4.+ versions.
What you have to do is give permission to the published folder/directory which your website points to
You have to add this user to the security section(folder properties) "IIS_IUSRS"
Give it at least the read/write permission
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2
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20
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19.04.2019
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India
visit: https://www.nopcommerce.com/boards/topic/57217/iis-not-finding-home-page-after-publishing-41#217695
this has solved my problem... which was same as yours