Nopcommerce page unresponsive

Hi,
I am using nopcommerce 4.5v.
I am getting issue of page unresponsive on product listing and edit page, Sometimes I am getting this issue on other pages also and page getting load for longer time. I am getting this only on UAT and Production.
Anyone have any idea?

I am trying to fix by :
- Clear cache (Browser, Nop).
- Delete wwwroot/bundles files.
- Change admin side AppSettings > Bundling Configuration.
- Increase app pool timeout.

https://prnt.sc/pZZhh_-Xpmgk

What is your server configuration and how many GB of RAM is allocated?
Do you have made any customization on the site?

Hi,
thanks for your reply.
32Gb RAM for two production sites. Yes, we have multiple customizations.

If you're not seeing errors in your System > Log, then it could be a browser problem.
Try incognito mode.
Try another browser.
If either of those work OK, then maybe your browser has a bad extension/plugin.

Alternately, it could be a firewall on your PC (e.g., Windows Defender firewall).
Try another PC

On top of the @New York comment, you could also try profiling the database to find out the long execution time of queries.
NopCommerce has a mini profiler so you can use it as a starting point. You will have to turn it on from the app settings page