A problem I have come across is the caching methodology in nopCommerce.
If a website is hosted on a cluster, the in memory cache becomes stale very quickly on high volume sites as each site has its own IIS worker process. A solution would be to add a simple dependancy, i.e a file dependancy which gets updated on an update/insert routine, therefore destroying the cache.
Would this be something others are interested in also? Clustered hosting is becoming more and more popular with companies such as Mosso/TSO etc all having clustered platforms.