I started a new install to test an upgrade path from 3.6 to 3.8. I installed 3.6 with the no source version and everything was fine. Applied the 3.7 script update and then updated the source and everything was fine. I then applied the 3.8 script and source and the public store is working fine but the admin area is having many issues. There appears to be no styling elements applying properly and many of the menu items do not work. There are no custom plugins or anything, this is a bare bones install and the server is full trust running on 2012 with IIS 8 and is fully updated as of today, .NET 4.5.1 is registered. Anyone have any ideas as to why this is happening? Here is a screen shot of what the Admin area looks like: